There are finally enough people visiting ChemFeeds (~150/day) that metrics like most accessed chemistry paper might actually be statistically significant information. So below I present the top two most clicked on abstracts from ChemFeeds for the first third of 2010.
2nd Place: Total Synthesis of the N,C-Coupled Naphthylisoquinoline Alkaloids Ancistrocladinium A and B and Related Analogues
by Gerhard Bringmann, Tanja Gulder†, Barbara Hertlein, Yasmin Hemberger and Frank Meyer in Journal of American Chemical Society
Some Notes on the metrics. This information probably says more about the people visiting ChemFeeds than the quality of the papers. It would appear ChemFeeds visitors skewer heavily towards the organic synthetics. Perhaps with the recent addition of being able to click on category feeds like all materials and all physical feeds it’ll balance out.