Chemistry Blog

Tag Archive: Derek Lowe

Feb 13

Hot news on an old story


Proposed structures of hexacyclinol

Some stories never seem to end. The hexacyclinol story is one of them. Is it over now? I assume most readers will be familiar with the controversy about the two proposed structures of hexacyclinol, the original one (1) and a revised one (2), and about a total synthesis of 1 by James LaClair that was …

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Jan 20

tert-Butyllithium Claims Fellow Chemist at UCLA


butyllithium

Story is from UCLA Newsroom (Jan 19th): A UCLA research assistant who was seriously burned in a laboratory fire last month has died of her injuries. The 22-year-old woman, whose name has not been released, died on Jan. 16 at Grossman Burn Center in Sherman Oaks. She was transferred there after initial treatment for second- …

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Dec 14

Diaza[12]annulene: Would You have Known Better?


The recent retraction of two papers regarding diaza[12]annulenes by Yamaguchi et al. and Shi et al. from separate groups have strengthened the argument for stronger peer review and more thorough literature review by authors. http://dx.doi.org/10.1002/anie.200704704 But anyone can be an armchair synthetic chemist and point fingers at what should have been done after the fact. …

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