Chemistry Blog

Tag Archive: Derek Lowe

Feb 13

Hot news on an old story


Some stories never seem to end. The hexacyclinol story is one of them. Is it over now? I assume most readers will be familiar with the controversy about the two proposed structures of hexacyclinol, the original one (1) and a revised one (2), and about a total synthesis of 1 by James LaClair that was …

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Jan 20

tert-Butyllithium Claims Fellow Chemist at UCLA


Story is from UCLA Newsroom (Jan 19th): A UCLA research assistant who was seriously burned in a laboratory fire last month has died of her injuries. The 22-year-old woman, whose name has not been released, died on Jan. 16 at Grossman Burn Center in Sherman Oaks. She was transferred there after initial treatment for second- …

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Dec 14

Diaza[12]annulene: Would You have Known Better?


The recent retraction of two papers regarding diaza[12]annulenes by Yamaguchi et al. and Shi et al. from separate groups have strengthened the argument for stronger peer review and more thorough literature review by authors. http://dx.doi.org/10.1002/anie.200704704 But anyone can be an armchair synthetic chemist and point fingers at what should have been done after the fact. …

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