Chemistry Blog

Tag Archive: Diels-Alder Reaction

Aug 22

Another Fascinating Structure and a Potent Anti-Cancer agent. (-)-FR 182877

(-)-FR 182877 and (-) FR 182876 are two structures isolated from Streptomyces sp. No.9885 by researchers at the Fujisawa Pharmaceutical company (now Astelllas)1-5. These compounds have been known for several years and the academic community has developed various approaches to their total synthesis, for example, references 6 and 7. Nakada etal8 became interested in the …

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