Post Tagged with: "JACS"

Introducing ChemFeeds your Graphical Abstracts Portal

Decided to make a new website, ChemFeeds, where you can view pretty graphical chemical abstracts from various sources like JACS, Angewandte, JOCS, OrgLett, and a whole host of others. It even has the Angewandte punsCBC, vis-à-vis OCB.

Feel free to roam around at the website, link is here:
http://www.chemfeeds.com/

Feedback and suggestions on how to make the website better and more useful for you, would be great.

Update 1: Permanent link can now be found in the top right header of this website. Which is an extension of the concept and scripts introduced here: Full Frontal JACS

Mitch

By October 22, 2008 1 comment chem 2.0

Problems with Aryl Enediyne Cyclizations?

Enediynes are lovely functional groups that are famous for undergoing Bergman cyclizations as shown below.

Scheme 1. Bergman cyclization.

Vavilala et al. have found an alternate reaction pathway for thermal enediyne cyclizations when bulky aryl groups are attached to the terminal ends; they observed indene formation.

Scheme 2. Pascal cyclization anyone?

Making indenes from enediynes is an old trick, either by photochemical or some exotic initiator, the caveat with this work is it runs under thermal conditions. The reaction they ran is shown below.

Scheme 3. Thermolysis (TCP = 2,4,6-trichlorophenyl)

No Bergman cyclization products were observed. The idea being, the distance of the terminal carbons (C1-C6) is crucial in determining which type of cyclization will occur. An interesting part of the paper is Matzger gets mentioned by name as a referee and as holding a different opinion of the authors, he basically argues the results are due to transfer hydrogenations from bergman cyclization intermediates. Definately an interesting read if you have time.

Link to paper: Thermal C1-C5 Diradical Cyclization of Enediynes

Mitch

By October 17, 2008 2 comments synthetic chemistry

Full Frontal JACS

The Journal of the American Chemical Society (JACS) has flirted with web 2.0 with it’s recent JACS β initiative. It has been warmly received around the blogosphere [CSB, TCB, CBC]. Although, I don’t have any complaints about the website, what I really wanted was less hand-holding and more of a shotgun approach to navigating through JACS online.

The nicest thing about thumbing through the print edition of JACS, is reading all the various chemistry that is outside your research tunnel-vision but still interesting.  If you go to the JACS homepage, here, you’ll see a list of 20 of the most recent articles, but not all of them! For example, 31 papers were added to ASAP today and only the last 20 are shown on their website, hardly a dire circumstance, but the fact is you miss some by using that setup. JACS also offers a nifty RSS feed of their articles, but I’ve never come across an RSS reader that’ll nicely format an active feed, 30+ submissions a day, in a format that will ever make me want to read it.

So how does one go about designing a more attractive JACS online browsing environment? Below is my attempt, it is as busy and attractive as a conference poster, but it lets you see a huge list of the most recently added papers to JACS ASAP.

 

The website parses through the JACS RSS feed. I was a bit worried about incorporating the graphical abstracts, but since they are included in the RSS feed, I’m going to claim fair use. The site isn’t pretty, but it gets the job done.

Here is a link for your viewing pleasure, Full Frontal JACS: http://www.chemfeeds.com/

Comments are always welcomed, but obviously this format is not for everyone.

Edit: A link to the site has been included in the links section to the right, towards the bottom under websites, titled Full Frontal JACS.

Update 1: Improved ACIE RSS feed

Update 2: Links edited to point to ChemFeeds instead of the simple script.

Mitch

By October 9, 2008 8 comments chem 2.0