Chemistry Blog

Tag Archive: Organic Lab Demonstrations

Apr 10

Chemistry Lab Demonstrations: Candy Chromatography


silicaspots

*For more cool stories, pictures, and videos of chemistry demonstrations, click here* Last lab of the semester today. Next week is the lab final and checkout. This week the students practiced column chromatography. They purified their crude product mixture from last week’s nitration lab. I’ve talked about the theory behind column chromatography before, so I …

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Apr 03

Chemistry Lab Demonstrations: Silver Nitrate/Copper Wire


nitration

*For more cool stories, pictures, and videos of chemistry demonstrations, click here* This week in lab, students performed electrophilic aromatic substitution (and here).  Dissolution of 4-methylacetanilide in 70% nitric acid gives mono nitration.  There are two possible products.  The acetamide is a better ortho/para director than the methyl group, so 2-nitro-4-methylacetanilide is the major product …

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Mar 27

Chemisry Lab Demonstrations: Nylon Rope Trick


amide

*For more cool stories, pictures, and videos of chemistry demonstrations, click here* This week’s lab involved taking the unknown carboxylic acid from experiments 1 (acid/base extraction) and 2 (purification by recrystallization) and converting it to a primary amide. The acid was refluxed in neat thionyl chloride and added dropwise to 30% ammonium hydroxide. Extract with …

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Mar 19

Chemistry Lab Demonstrations: Homemade Breathylizers…Sorta


bromocresolgreen

*For more cool stories, pictures, and videos of chemistry demonstrations, click here* Undergrads were on spring break last week, so no lab last week.  This week, we performed the Jones oxidation of isoborneol to camphor.  The crude product was put in the bottom of a Hirsch funnel with a cold finger, and the product was …

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Mar 05

Chemistry Lab Demonstrations – Silver Mirror


hwe

*For more cool stories, pictures, and videos of chemistry demonstrations, click here* This week’s reaction was the HWE-modified Wittig reaction (and here) between para-anisaldeyhde and triethyl phosphonoacetate.  Saponification, followed by recrystallization of the acidified product gives nice needles of p-methoxycinnamic acid.  Funny thing, though, p-methoxycinnamic acid is supposed to be a white solid.  Half of …

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Feb 25

Chemistry Lab Demonstrations – Dehydrating Sugar


*For more cool stories, pictures, and videos of chemistry demonstrations, click here* This week, the organic chemistry lab I’m TA’ing dehydrated 2-methylcyclohexanol with phosphoric acid to give a mixture of 1- and 3-methylcyclohexene.  The product ratio was determined by GC analysis… At least it was supposed to be.  The students for the most part did …

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